2025 was a big year for Korean skin care, and an even bigger year for PDRN!
The cult-favorite ingredient that was once an exclusive Hollywood injectable treatment is now in many Korean skin care products including serums, ampoules, moisturizers and face masks.
PDRN, or polydeoxyribonucleotide, are DNA fragments derived from salmon sperm cells and prized for its regenerative properties. Since its boom, vegan PDRN alternatives have also emerged, derived from plant ingredients like centella asiatica, ginseng and rice.
What are the benefits of PDRN?
- Boosts skin regeneration: PDRN stimulates skin cell growth, promoting the skin’s natural repair process.
- Strengthens the skin barrier: PDRNsupports skin health by fortifying your skin and guarding it against environmental stressors.
- Improves skin elasticity: By stimulating collagen production, PDRN firms skin for a plump and youthful finish.
Read on to discover ten of the best Korean PDRN skin care products!
medicube – PDRN Pink Peptide Serum
Unless you’ve been living under a rock, you’ve probably seen (or tried) this viral PDRN Pink Peptide Serum from medicube. Formulated with salmon PDRN, peptides and hydrolyzed collagen, the serum firms your skin to minimize fine lines and wrinkles. It’s also infused with niacinamide and turmeric root extract to fade dark spots and brighten skin tone for that glass skin glow!
VT – PDRN Essence 100
VT’s all-rounder essence checks all the boxes from boosting skin elasticity to restoring hydration to strengthening the skin barrier. The rich, milky formula revitalizes skin with low-molecular PDRN derived from Korean ginseng, along with five types of ceramides to nourish skin. You’ll love the glow and softened skin texture it gives your skin with ingredients like polyglucuronic acid and panthenol!
Anua – PDRN Hyaluronic Acid Capsule 100 Serum
This bestselling Anua serum gives your skin the ultimate hydration and anti-wrinkle boost with PDRN, hydrolyzed collagen and 11 types of hyaluronic acid. Ideal for dry and mature skin types, the bright blue formula strengthens the skin’s moisture barrier too. Anua’s Smart Capsule technology promotes the absorption of these active ingredients into your skin for optimal skin benefits.
HEVEBLUE – Salmon Caring Centella Cream
This bouncy, jelly-like cream from HEVEBLUE features star ingredients centella asiatica leaf water, salmon PDRN and salmon roe extract to soothe sensitive skin and fortify the skin barrier. Low-molecular hyaluronic acid and HEVEBLUE’s patented EFFIPULP (avocado-derived peptide) locks in moisture while giving your skin that refreshing dewy finish. The gentle cream is suitable for all skin types including sensitive skin.
Abib – PDRN Collagen Lip Mask Glazed Jelly
Naturally dewy lips come easy with Abib’s Lip Mask Glazed Jelly enriched with moisturizing and elasticity care ingredients like centella-derived PDRN and hyaluronic acid. The bouncy, jelly-like formula nourishes the lips with rice extract rich in amino acids. Apply the glazed lip mask overnight and wake up to baby-soft lips in the morning!
numbuzin – No.9 NAD+ PDRN Glow Boosting Toner
With ingredients like salmon PDRN, NAD+ and a whopping 50 types of peptides that boost skin renewal, this glow-boosting toner from numbuzin is a mighty antidote to skin aging! Boasting a natural shimmery violet hue from ceramides and Vitamin B12, the toner soothes and hydrates skin while minimizing fine lines, wrinkles and enlarged pores.
Genabelle – PDRN Rejuvenating Toner
If you’re not yet sold on the regenerative properties of PDRN, take it from Genabelle, one of the first pioneers of PDRN in the K-Beauty world. This hydrating toner smooths skin texture and strengthens the skin barrier with the brand’s patented HTD-GENACOMPLEX™ formulated with salmon PDRN and three types of hyaluronic acid. It also gives your skin ample nourishment with Vitamins B and E. Mature skin types will love its array of benefits from brightening skin tone with niacinamide to smoothing fine lines and wrinkles with its blend of anti-agers.
medicube – PDRN Pink Collagen Gel Mask
Rich in salmon PDRN, low-molecular hydrolyzed collagen and peptides, this mask reduces fine lines while fortifying your skin barrier. Gain a powerful boost in skin elasticity and a brighter skin tone thanks to ingredients like niacinamide and adenosine. After application, the pretty pink mask turns transparent once the essence has fully absorbed in skin, delivering multiple skin benefits.
mixsoon – PDRN Collagen Eye Serum
mixsoon’s eye serum is enriched with plant-based PDRN, low-molecular collagen and liposomal peptides – just what you need to pep up dull, tired eyes. The lightweight, creamy texture absorbs effortlessly into the eye area, minimizing fine lines while being gentle on delicate eye skin. Added with fermented rice bran and hyaluronic acid, the eye serum brightens skin tone while leaving a hydrating finish.
EQQUALBERRY – Purple PDRN Pore Minimizing Serum
Boost skin elasticity and minimize enlarged pores with EQQUALBERRY’s Purple PDRN Pore Minimizing Serum. Infused with rice-derived PDRN and other favorite anti-aging ingredients like collagen, peptides and elastin, the milky formula gives skin a firming boost. The serum regulates sebum production with tannin complex and LHA, while other actives like hyaluronic acid, panthenol and ceramides boost skin hydration.
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